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A trio of mercenaries investigate a secret organisation turning young women into invincible assassins. With the aid of a former spy, they take it upon themselves to destroy the evil syndicate behind the conspiracy.
The Rhodium Golems - three soldiers of fortune composed of sympathetic pilot Vincenzo Corbucci, pragmatic rifleman Nikolai Rostavili, and Machiavellian medic Jacques Dubois - uncover a dark secret when they awaken ex-assassin Hiroka Noguchi from cryogenic stasis during a routine scavenging mission. They learn that she and her friend Elsa Lindblom were brainwashed to become human killing machines as part of Project Athena, a controversial experiment to create the ultimate warrior. With Hiroka's help, the mercenaries travel the globe to find out more about the 5 Elements, a powerful organisation with ties to Project Athena, and to rescue Elsa from the influence of sociopathic researcher Sorina Manescu. In a parallel storyline, Elsa's brother, Erik, gets close to the organisation's heiress Yasmin Salibi in order to find out what happened to his sister.