Pursued by deadly space kittens, the cosmos’s most notorious idiot and his nephew find a hidden stash of weed during their efforts to save the last members of a dying race of alien pugs.
The year is far into the future. Earth is a galactic legend and no humans have been there for many millennia. While being chased by a race of bipedal cats, a group of space-pugs enlists Buddy & Colton's help and they discover an ancient space myth: Mary Jane. As they travel the stars to save the day they test the myth and get "galactically high" in the process. Now, the fate of the pugs and the galaxy is threatened by angry cats, and their only hope rests on a half-wit to deliver some weed.